Toll-like Receptor Status in Obesity and Metabolic Syndrome: A Translational Perspectiv... - 0 views
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Nathan Goodyear on 06 Jan 14Only the abstract is available publicly. Toll-like receptors, particularly TLR-4 has been shown to be associated with insulin resistance. These TLRs have specific pathogen recognition sites. TLRs are stimulated by fatty acids (FA) and endotoxemia from bacteria. Thus, dietary intake of high trans fats, inflammation originating from the gut can be the source of insulin receptor dysfunction through TLRs.